Jessica Perrin

Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

Marcus Bantscheff, Dirk Eberhard, Yann Abraham et al. · Nature Biotechnology · 2007 · 1K citations

Quantitative Chemical Proteomics, Biochemistry, Medicine +9

Identifying drug targets in tissues and whole blood with thermal-shift profiling

Jessica Perrin, Thilo Werner, Nils Kurzawa et al. · Nature Biotechnology · 2020 · 187 citations

Drug Target, Hit Identification, Medicine +12

A selective inhibitor reveals PI3Kγ dependence of TH17 cell differentiation

Giovanna Bergamini, Kathryn M. Bell, Satoko Shimamura et al. · Nature Chemical Biology · 2012 · 143 citations

Signal Transduction, Signaling Pathway, Cell Regulation +7

Chemical Proteomics Reveals Ferrochelatase as a Common Off-target of Kinase Inhibitors

Susan Klaeger, Jessica Perrin, Vipul Gupta et al. · ACS Chemical Biology · 2016 · 103 citations · Full text

Signal Transduction Pathways, Drug Target, Chemoprevention Strategy +20

Discovery of GSK8612, a Highly Selective and Potent TBK1 Inhibitor

Douglas W. Thomson, Daniel Poeckel, Nico Zinn et al. · ACS Medicinal Chemistry Letters · 2019 · 87 citations · Full text

Immune Regulation, Immunology, Immunologic Mechanism +24