Christopher P. Tinworth

PROTAC-Mediated Degradation of Bruton’s Tyrosine Kinase Is Inhibited by Covalent Binding

Christopher P. Tinworth, Hannah Lithgow, Lars Dittus et al. · ACS Chemical Biology · 2019 · 175 citations

Molecular Regulation, Molecular Biology, Reversible Binding Protacs +25

Facts, Patterns, and Principles in Drug Discovery: Appraising the Rule of 5 with Measured Physicochemical Data

Christopher P. Tinworth, Robert J. Young · Journal of Medicinal Chemistry · 2020 · 118 citations

Structural Insights into PROTAC-Mediated Degradation of Bcl-xL

Chun‐wa Chung, Han Dai, Esther Fernández et al. · ACS Chemical Biology · 2020 · 86 citations

Light-mediated multi-target protein degradation using arylazopyrazole photoswitchable PROTACs (AP-PROTACs)

Qisi Zhang, Cyrille S. Kounde, Milon Mondal et al. · Chemical Communications · 2022 · 45 citations · Full text

Photobiology, Molecular Biology, Unique Photoswitchable Protac +16

Targeting the Regulatory Site of ER Aminopeptidase 1 Leads to the Discovery of a Natural Product Modulator of Antigen Presentation

John Liddle, Jonathan P. Hutchinson, Semra Kitchen et al. · Journal of Medicinal Chemistry · 2020 · 43 citations · Full text