Concepedia

Christopher P. Tinworth

CP

Statistics

Publications

9

Citations

564

H-Index

9

Active since

2016

Affiliations

GlaxoSmithKline (United Kingdom)(Current)

Age UK

GlaxoSmithKline (United States)

University of Leeds

South College

Christopher P. Tinworth is an author at GlaxoSmithKline (United Kingdom) specializing in pharmacology, drug discovery, and life sciences.

ORCID

Publications per year

2016–2023

9

Publications

9

PROTAC-Mediated Degradation of Bruton’s Tyrosine Kinase Is Inhibited by Covalent Binding

Christopher P. Tinworth, Hannah Lithgow, Lars Dittus et al. · ACS Chemical Biology · 2019 · 182 citations

, , +17

Facts, Patterns, and Principles in Drug Discovery: Appraising the Rule of 5 with Measured Physicochemical Data

Christopher P. Tinworth, Robert J. Young · Journal of Medicinal Chemistry · 2020 · 120 citations

, , +17

Structural Insights into PROTAC-Mediated Degradation of Bcl-xL

Chun‐wa Chung, Han Dai, Esther Fernández et al. · ACS Chemical Biology · 2020 · 88 citations

, , +15

Light-mediated multi-target protein degradation using arylazopyrazole photoswitchable PROTACs (AP-PROTACs)

Qisi Zhang, Cyrille S. Kounde, Milon Mondal et al. · Chemical Communications · 2022 · 52 citations · Full text

, , +11

Targeting the Regulatory Site of ER Aminopeptidase 1 Leads to the Discovery of a Natural Product Modulator of Antigen Presentation

John Liddle, Jonathan P. Hutchinson, Semra Kitchen et al. · Journal of Medicinal Chemistry · 2020 · 45 citations · Full text

, , +17

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