Serge A.L. Zander

High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs

Sven Rottenberg, Janneke E. Jaspers, Ariena Kersbergen et al. · Proceedings of the National Academy of Sciences · 2008 · 949 citations · Full text

Medicine, Oncology, Pharmacology +16

Loss of 53BP1 Causes PARP Inhibitor Resistance in <i>Brca1</i> -Mutated Mouse Mammary Tumors

Janneke E. Jaspers, Ariena Kersbergen, Ute Boon et al. · Cancer Discovery · 2012 · 515 citations · Full text

Medicine, Oncology, Pharmacology +17

Blebs produced by actin–myosin contraction during apoptosis release damage-associated molecular pattern proteins before secondary necrosis occurs

Grant Wickman, Linda Julian, Katerina Mardilovich et al. · Cell Death and Differentiation · 2013 · 194 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Sensitivity and Acquired Resistance of BRCA1;p53-Deficient Mouse Mammary Tumors to the Topoisomerase I Inhibitor Topotecan

Serge A.L. Zander, Ariena Kersbergen, Eline van der Burg et al. · Cancer Research · 2010 · 85 citations

Medicine, Oncology, Pharmacology +17

Impact of Intertumoral Heterogeneity on Predicting Chemotherapy Response of BRCA1-Deficient Mammary Tumors

Sven Rottenberg, Marieke A. Vollebergh, Bas de Hoon et al. · Cancer Research · 2012 · 51 citations · Full text

Life Sciences, Molecular Biology, Oncology +17