Concepedia

Vishal Thapar

VT

25

Publications

7.1K

Citations

22

H-Index

2005

Active since

Affiliations

Massachusetts General Hospital(Current)

Harvard University

Memorial Sloan Kettering Cancer Center

Howard Hughes Medical Institute

University of Connecticut

Vishal Thapar is an author at Massachusetts General Hospital specializing in medicine, systems biology, and computational biology.

Top concepts

MedicineSystems BiologyBioinformaticsComputational BiologyEngineeringTumor BiologyRadiation OncologyCell BiologyCancer ResearchTumor Microenvironment

Publications per year

2005–2022

25

Publications

25

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

Shengdar Q. Tsai, Zongli Zheng, Nathalie T. Nguyen et al. · Nature Biotechnology · 2014 · 2.2K citations · Full text

Off-target Effect, Genetics, Gene Editing +7

Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

Shengdar Q. Tsai, Nicolas Wyvekens, Cyd Khayter et al. · Nature Biotechnology · 2014 · 961 citations · Full text

Non-Cell-Autonomous Tumor Suppression by p53

Amaia Lujambio, Leila Akkari, Janelle Simon et al. · Cell · 2013 · 730 citations · Full text

Non-cell-autonomous Tumor Suppression, Malignant Disease, Tumor Suppressor +4

Stromal Microenvironment Shapes the Intratumoral Architecture of Pancreatic Cancer

Matteo Ligorio, Srinjoy Sil, Jose Malagon-Lopez et al. · Cell · 2019 · 519 citations · Full text

Pancreatic Cancer, Biological Microenvironments, Medicine +3

EWS-FLI1 Utilizes Divergent Chromatin Remodeling Mechanisms to Directly Activate or Repress Enhancer Elements in Ewing Sarcoma

Nicolò Riggi, Birgit Knoechel, Shawn Gillespie et al. · Cancer Cell · 2014 · 452 citations · Full text

Chromatin, Ewing Sarcoma, Chromatin Remodeling +6

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