Sandra Leitza

Novel <i>p</i>-Arylthio Cinnamides as Antagonists of Leukocyte Function-Associated Antigen-1/Intracellular Adhesion Molecule-1 Interaction. 2. Mechanism of Inhibition and Structure-Based Improvement of Pharmaceutical Properties

Gang Liu, Jeffrey R. Huth, Edward T. Olejniczak et al. · Journal of Medicinal Chemistry · 2001 · 354 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Discovery of Novel <i>p</i>-Arylthio Cinnamides as Antagonists of Leukocyte Function-Associated Antigen-1/Intracellular Adhesion Molecule-1 Interaction. 1. Identification of an Additional Binding Pocket Based on an Anilino Diaryl Sulfide Lead

Gang Liu, J. T. Link, Zhonghua Pei et al. · Journal of Medicinal Chemistry · 2000 · 218 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

The [3H]dofetilide binding assay is a predictive screening tool for hERG blockade and proarrhythmia: Comparison of intact cell and membrane preparations and effects of altering [K+]o

Gilbert Diaz, Katina Daniell, Sandra Leitza et al. · Journal of Pharmacological and Toxicological Methods · 2004 · 118 citations

Medicine, Cardiology, Pharmacology +16

Discovery of Novel <i>p</i>-Arylthio Cinnamides as Antagonists of Leukocyte Function-Associated Antigen-1/Intercellular Adhesion Molecule-1 Interaction. 4. Structure−Activity Relationship of Substituents on the Benzene Ring of the Cinnamide

Martin Winn, Edward B. Reilly, Gang Liu et al. · Journal of Medicinal Chemistry · 2001 · 59 citations · Full text

Life Sciences, Immunology, Pharmacology +16

Discovery of Potent Antagonists of Leukocyte Function-Associated Antigen-1/Intercellular Adhesion Molecule-1 Interaction. 3. Amide (C-Ring) Structure−Activity Relationship and Improvement of Overall Properties of Arylthio Cinnamides

Zhonghua Pei, Zhili Xin, Gang Liu et al. · Journal of Medicinal Chemistry · 2001 · 28 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17