Jonathan J. Hulce

Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells

Jonathan J. Hulce, Armand B. Cognetta, Micah J. Niphakis et al. · Nature Methods · 2013 · 446 citations

Life Sciences, Biochemistry, Molecular Biology +16

A road map to evaluate the proteome-wide selectivity of covalent kinase inhibitors

Bryan Lanning, Landon R. Whitby, Melissa M. Dix et al. · Nature Chemical Biology · 2014 · 363 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +15

Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue

Wentao Chen, Jiajia Dong, Lars Plate et al. · Journal of the American Chemical Society · 2016 · 294 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs

William H. Parsons, Matthew J. Kolar, Siddhesh S. Kamat et al. · Nature Chemical Biology · 2016 · 86 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Selective blockade of the lyso-PS lipase ABHD12 stimulates immune responses in vivo

Daisuke Ogasawara, Taka-Aki Ichu, Vincent F. Vartabedian et al. · Nature Chemical Biology · 2018 · 72 citations

Life Sciences, Biochemistry, Immunology +11