Matthew J. Kolar

Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models

Robert Svensson, Seth J. Parker, Lillian J. Eichner et al. · Nature Medicine · 2016 · 520 citations

Medicine, Biochemistry, Oncology +17

Gpr132 sensing of lactate mediates tumor–macrophage interplay to promote breast cancer metastasis

Peiwen Chen, Hao Zuo, Hu Xiong et al. · Proceedings of the National Academy of Sciences · 2017 · 505 citations · Full text

Medicine, Cancer Biology, Oncology +17

Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence

Gabriele Sulli, Amy Rommel, Xiaojie Wang et al. · Nature · 2018 · 410 citations

Medicine, Cancer Biology, Oncology +11

Metformin Inhibits Hepatic mTORC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex

Jessica J. Howell, Kristina Hellberg, Marc Turner et al. · Cell Metabolism · 2017 · 405 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14

SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism

Yumiko Oishi, Nathanael J. Spann, Verena M. Link et al. · Cell Metabolism · 2016 · 342 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14