Lukas Schmidheini

In vivo prime editing of a metabolic liver disease in mice

Desirée Böck, Tanja Rothgangl, Lukas Villiger et al. · Science Translational Medicine · 2022 · 173 citations · Full text

Predicting prime editing efficiency and product purity by deep learning

Nicolas Mathis, Ahmed Allam, Lucas Kissling et al. · Nature Biotechnology · 2023 · 129 citations · Full text

Artificial Intelligence, Product Purity, Engineering +5

Machine learning prediction of prime editing efficiency across diverse chromatin contexts

Nicolas Mathis, Ahmed Allam, András Tálas et al. · Nature Biotechnology · 2024 · 46 citations · Full text

Continuous directed evolution of a compact CjCas9 variant with broad PAM compatibility

Lukas Schmidheini, Nicolas Mathis, Kim Fabiano Marquart et al. · Nature Chemical Biology · 2023 · 40 citations · Full text

Broad Pam Compatibility, Computer Engineering, Compact Cjcas9 Variant

Dark-Field Microwells toward High-Throughput Direct miRNA Sensing with Gold Nanoparticles

Stéphanie Hwu, Yves Blickenstorfer, Raphael F. Tiefenauer et al. · ACS Sensors · 2019 · 33 citations