András Tálas

Improved LbCas12a variants with altered PAM specificities further broaden the genome targeting range of Cas12a nucleases

Eszter Tóth, Éva Varga, Péter István Kulcsár et al. · Nucleic Acids Research · 2020 · 160 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Crossing enhanced and high fidelity SpCas9 nucleases to optimize specificity and cleavage

Péter István Kulcsár, András Tálas, Krisztina Huszár et al. · Genome biology · 2017 · 129 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Mb- and FnCpf1 nucleases are active in mammalian cells: activities and PAM preferences of four wild-type Cpf1 nucleases and of their altered PAM specificity variants

Eszter Tóth, Bernadett C Czene, Péter István Kulcsár et al. · Nucleic Acids Research · 2018 · 78 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Cpf1 nucleases demonstrate robust activity to induce DNA modification by exploiting homology directed repair pathways in mammalian cells

Eszter Tóth, Nóra Weinhardt, Petra Bencsura et al. · Biology Direct · 2016 · 63 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Machine learning prediction of prime editing efficiency across diverse chromatin contexts

Nicolas Mathis, Ahmed Allam, András Tálas et al. · Nature Biotechnology · 2024 · 57 citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +12