Concepedia

Christine Stephan

CS

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Publications

15

Citations

2.2K

H-Index

12

Active since

1992

Affiliations

Novartis (Switzerland)(Current)

Novartis Institutes for BioMedical Research

Friedrich Miescher Institute

University of Cincinnati

Christine Stephan is an author at Novartis (Switzerland) specializing in medicine, natural sciences, and cell biology.

Top concepts

Publications per year

1992–2022

15

Publications

15

Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening

E. Robert McDonald, Antoine de Weck, Michael R. Schlabach et al. · Cell · 2017 · 687 citations · Full text

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Antitumor Efficacy of Intermittent Treatment Schedules with the Rapamycin Derivative RAD001 Correlates with Prolonged Inactivation of Ribosomal Protein S6 Kinase 1 in Peripheral Blood Mononuclear Cells

Anne Boulay, Sabine Zumstein-Mecker, Christine Stephan et al. · Cancer Research · 2004 · 319 citations · Full text

Increased AKT S473 phosphorylation after mTORC1 inhibition is rictor dependent and does not predict tumor cell response to PI3K/mTOR inhibition

Madlaina Breuleux, Matthieu Klopfenstein, Christine Stephan et al. · Molecular Cancer Therapeutics · 2009 · 240 citations · Full text

Identifying Optimal Biologic Doses of Everolimus (RAD001) in Patients With Cancer Based on the Modeling of Preclinical and Clinical Pharmacokinetic and Pharmacodynamic Data

Chiaki Tanaka, Terence O’Reilly, John M. Kovarik et al. · Journal of Clinical Oncology · 2008 · 209 citations

Role of mitochondria and C‐terminal membrane anchor of Bcl‐2 in Bax induced growth arrest and mortality in <i>Saccharomyces cerevisiae</i>

William Greenhalf, Christine Stephan, Bhabatosh Chaudhuri · FEBS Letters · 1996 · 178 citations · Full text

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