INCB054828 (pemigatinib), a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3, displays activity against genetically defined tumor models

Phillip C.C. Liu, Holly K. Koblish, Liangxing Wu, +24

PLoS ONE

Fgfr AlterationsMedicinePharmacologySelective InhibitorPathology +12

Ghrelin and cholecystokinin in term and preterm human breast milk

Jennifer A. Kierson, Darlise DiMatteo, Robert Locke, +2

Acta Paediatrica

Leptin Enhances Lung Maturity in the Fetal Rat

Susan M. Kirwin, Vineet Bhandari, Darlise DiMatteo, +7

Pediatric Research

Fetal RatDevelopmental BiologyPhysiologyHypothalamic PeptideEndocrinology +2

The Novel Bromodomain and Extraterminal Domain Inhibitor INCB054329 Induces Vulnerabilities in Myeloma Cells That Inform Rational Combination Strategies

Matthew C. Stubbs, Timothy C. Burn, Richard Sparks, +33

Clinical Cancer Research

Genetic conversion of an SMN2 gene to SMN1: A novel approach to the treatment of spinal muscular atrophy

Darlise DiMatteo, Stephanie Callahan, Eric B. Kmiec

Experimental Cell Research

Genetic ConversionGene TherapiesRare DiseasesGenetic DisorderGenetics +7

Discovery of INCA033989, a Monoclonal Antibody That Selectively Antagonizes Mutant Calreticulin Oncogenic Function in Myeloproliferative Neoplasms (MPNs)

Edimara S. Reis, Rebecca A. Buonpane, Hamza Celik, +13

Blood

Selective targeting of mutated calreticulin by the monoclonal antibody INCA033989 inhibits oncogenic function of MPN

Edimara S. Reis, Rebecca A. Buonpane, Hamza Celik, +32

Blood

Increased susceptibility of spinal muscular atrophy fibroblasts to camptothecin-induced cell death

Wenlan Wang, Darlise DiMatteo, Vicky L. Funanage, +1

Molecular Genetics and Metabolism

Spinal Cord InjuryApoptosisCell DeathPathologyDegenerative Disease +6

Abstract 3523: Discovery of a novel BET inhibitor INCB054329

Phillip CC Liu, Xuesong Mike Liu, Matthew C. Stubbs, +24

Cancer Research

ImmunologyMolecular BiologyImmunotherapyCancer BiologyTumor Biology +18

Abstract 771: Preclinical characterization of the selective FGFR inhibitor INCB054828

Phillip CC Liu, Liangxing Wu, Holly K. Koblish, +20

Cancer Research

Molecular PharmacologyTumor BiologyFgfr AlterationsMedicineAbstract 771 +13