Jidong Zhu

Targeting MLL1 H3K4 Methyltransferase Activity in Mixed-Lineage Leukemia

Fang Cao, Elizabeth C. Townsend, Hacer Karataş et al. · Molecular Cell · 2014 · 296 citations · Full text

Hematological Malignancy, Chromatin, Mixed-phenotype Acute Leukemia +6

Phase Separation of Disease-Associated SHP2 Mutants Underlies MAPK Hyperactivation

Guangya Zhu, Jingjing Xie, Wenna Kong et al. · Cell · 2020 · 260 citations · Full text

Signal Transduction, Molecular Physiology, Signaling Pathway +5

Activation of PI3K/Akt and MAPK pathways regulates Myc-mediated transcription by phosphorylating and promoting the degradation of Mad1

Jidong Zhu, John Blenis, Junying Yuan · Proceedings of the National Academy of Sciences · 2008 · 244 citations · Full text

Myc-mediated Transcription, Systems Biology, Signal Transduction +15

Histone methyltransferase SETDB1 regulates liver cancer cell growth through methylation of p53

Qi Fei, Ke Shang, Jianhua Zhang et al. · Nature Communications · 2015 · 161 citations · Full text

Histone Modifications, Epigenetic Change, Epigenetics +16

Targeting androgen receptor phase separation to overcome antiandrogen resistance

Jingjing Xie, Hao He, Wenna Kong et al. · Nature Chemical Biology · 2022 · 143 citations

Antiandrogen Resistance, Medicine, Hormonal Receptor +4