David Mangan

Biocatalytic reductive amination from discovery to commercial manufacturing applied to abrocitinib JAK1 inhibitor

Rajesh Kumar, Michael J. Karmilowicz, Dylan Burke et al. · Nature Catalysis · 2021 · 129 citations

Medicinal Chemistry, Engineering, Commercial Manufacturing +10

Hydrolysis of wheat flour arabinoxylan, acid-debranched wheat flour arabinoxylan and arabino-xylo-oligosaccharides by β-xylanase, α-l-arabinofuranosidase and β-xylosidase

Barry V. McCleary, Vincent A. McKie, Anna Draga et al. · Carbohydrate Research · 2015 · 86 citations

Food Chemistry, Biosynthesis, Engineering +7

Overcoming Equilibrium Issues with Carbonyl Reductase Enzymes

Susan J. Calvin, David Mangan, Iain Miskelly et al. · Organic Process Research & Development · 2011 · 48 citations

Engineering, Organic Chemistry, Redox Biology +17

A novel enzymatic method for the measurement of lactose in lactose‐free products

David Mangan, Barry V. McCleary, Helena Culleton et al. · Journal of the Science of Food and Agriculture · 2018 · 42 citations · Full text

A Three‐Enzyme System Involving an Ene‐Reductase for Generating Valuable Chiral Building Blocks

David Mangan, Iain Miskelly, Thomas S. Moody · Advanced Synthesis & Catalysis · 2012 · 29 citations

Asymmetric Catalysis, Renewable Alternative, Engineering +11