Concepedia

Lan-Zhen Wang

LW

17

Publications

1.3K

Citations

16

H-Index

2002

Active since

Affiliations

Newcastle University(Current)

Cancer Research UK

Babraham Institute

Pfizer (United States)

Lan-Zhen Wang is an author at Newcastle University specializing in medicine, drug discovery, and pharmacology.

Top concepts

Publications per year

2002–2021

17

Publications

17

Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial

Huw D. Thomas, Christopher Calabrese, Michael A. Batey et al. · Molecular Cancer Therapeutics · 2007 · 297 citations

Novel Poly(ADP-ribose) Polymerase-1 Inhibitor, AG14361, Restores Sensitivity to Temozolomide in Mismatch Repair-Deficient Cells

Nicola J. Curtin, Lan-Zhen Wang, Anthie Yiakouvaki et al. · Clinical Cancer Research · 2004 · 164 citations

Differences in the Conformational Energy Landscape of CDK1 and CDK2 Suggest a Mechanism for Achieving Selective CDK Inhibition

D.J. Wood, S. Korolchuk, Natalie J. Tatum et al. · Cell chemical biology · 2018 · 137 citations · Full text

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Novel Tricyclic Poly(ADP-ribose) Polymerase-1 Inhibitors with Potent Anticancer Chemopotentiating Activity:  Design, Synthesis, and X-ray Cocrystal Structure

Stacie S. Canan Koch, Lars Thoresen, Jayashree Tikhe et al. · Journal of Medicinal Chemistry · 2002 · 134 citations · Full text

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N<sup>2</sup>-Substituted <i>O</i><sup>6</sup>-Cyclohexylmethylguanine Derivatives:  Potent Inhibitors of Cyclin-Dependent Kinases 1 and 2

Ian R. Hardcastle, Christine E. Arris, Johanne Bentley et al. · Journal of Medicinal Chemistry · 2004 · 122 citations · Full text

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