Charles W. Mann

Preparative separation and identification of derivatized β-methylphenylalanine enantiomers by chiral SFC, HPLC and NMR for development of new peptide ligand mimetics in drug discovery

Lisa Nogle, Charles W. Mann, William L. Watts et al. · Journal of Pharmaceutical and Biomedical Analysis · 2005 · 45 citations

Medicinal Chemistry, Biochemistry, Medicine +10

Discovery of a novel series of Notch-sparing γ-secretase inhibitors

Anthony F. Kreft, Boyd L. Harrison, Suzan Aschmies et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 25 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Medicine +7

(S)-N-(5-Chlorothiophene-2-sulfonyl)-β,β-diethylalaninol a Notch-1-sparing γ-secretase inhibitor

Derek C. Cole, Joseph R. Stock, Anthony F. Kreft et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 19 citations

Molecular Pharmacology, Medicinal Chemistry, Inhibitory Activity +10

Discovery of Novel Selective Norepinephrine Reuptake Inhibitors: 4-[3-Aryl-2,2-dioxido-2,1,3-benzothiadiazol-1(3<i>H</i>)-yl]-1-(methylamino)butan-2-ols (WYE-103231)

David J. O’Neill, Adedayo Adedoyin, Peter D. Alfinito et al. · Journal of Medicinal Chemistry · 2010 · 17 citations · Full text

Discovery of 6-({4-[2-(4-<i>tert</i>-Butylphenyl)-1<i>H</i>-benzimidazol-4-yl]piperazin-1-yl}methyl)quinoxaline (WAY-207024): An Orally Active Antagonist of the Gonadotropin Releasing Hormone Receptor (GnRH-R)

Jeffrey C. Pelletier, Murty Chengalvala, Joshua E. Cottom et al. · Journal of Medicinal Chemistry · 2009 · 15 citations · Full text

Pharmaceutical Science, Pharmacotherapy, Pharmaceutical Chemistry +17