Megan T. Hoffman

Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer

Nina G. Steele, Giulia Biffi, Samantha B. Kemp et al. · Clinical Cancer Research · 2021 · 265 citations · Full text

Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer

Julien Dilly, Megan T. Hoffman, Laleh Abbassi et al. · Cancer Discovery · 2024 · 182 citations · Full text

Kras Inhibitors, Pancreatic Cancer, Oncogenic Agent +13

MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance

Amy Farrell, Meghan M. Joly, Brittany L. Allen-Petersen et al. · Nature Communications · 2017 · 157 citations · Full text

Lineage Plasticity, Pancreatic Cancer, Poor Outcome +14

Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer

Min-Sik Lee, Courtney Dennis, Insia Naqvi et al. · Nature · 2023 · 113 citations · Full text

Pancreatic Cancer, Ornithine Aminotransferase, Oncogenic Agent +3

Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context

Samuel A. Kerk, Lin Lin, Amy L. Myers et al. · eLife · 2022 · 110 citations · Full text

Pathology, Environmental Context, Metabolic Remodeling +23