Multimodal mapping of the tumor and peripheral blood immune landscape in human pancreatic cancer

Nina G. Steele, Eileen S. Carpenter, Samantha B. Kemp, +36

Nature Cancer

Cancer ImmunosurveillancePancreatic CancerImmunologyTumor ImmunityPathology +7

Regulatory T-cell Depletion Alters the Tumor Microenvironment and Accelerates Pancreatic Carcinogenesis

Yaqing Zhang, Jenny Lazarus, Nina G. Steele, +20

Cancer Discovery

Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity

Colin Hutton, Felix Heider, Adrián Blanco‐Gómez, +24

Cancer Cell

Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer

Nina G. Steele, Giulia Biffi, Samantha B. Kemp, +33

Clinical Cancer Research

Apolipoprotein E Promotes Immune Suppression in Pancreatic Cancer through NF-κB–Mediated Production of CXCL1

Samantha B. Kemp, Eileen S. Carpenter, Nina G. Steele, +15

Cancer Research

Hedgehog transcriptional effector GLI mediates mTOR-Induced PD-L1 expression in gastric cancer organoids

Vivien Koh, Jayati Chakrabarti, Meaghan Torvund, +11

Cancer Letters

Gastric Cancer OrganoidsMtor-induced Pd-l1 ExpressionTranscriptional RegulationSignal TransductionSignaling Pathway +8

An Organoid-Based Preclinical Model of Human Gastric Cancer

Nina G. Steele, Jayati Chakrabarti, Jiang Wang, +12

Cellular and Molecular Gastroenterology and Hepatology

Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages

Samantha B. Kemp, Nina G. Steele, Eileen S. Carpenter, +21

Life Science Alliance

Hedgehog signaling induces PD-L1 expression and tumor cell proliferation in gastric cancer

Jayati Chakrabarti, Loryn Holokai, Li-Jyun Syu, +6

Oncotarget

Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context

Samuel A. Kerk, Lin Lin, Amy L. Myers, +28

eLife

PathologyEnvironmental ContextMetabolic RemodelingRedox HomeostasisTumor Biology +21