Samuel A. Kerk

Reuterin in the healthy gut microbiome suppresses colorectal cancer growth through altering redox balance

Hannah N. Bell, Ryan J. Rebernick, Joshua Goyert et al. · Cancer Cell · 2021 · 287 citations · Full text

Medicine, Cancer Biology, Oncology +12

GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis

Daniel M. Kremer, Barbara Scott Nelson, Lin Lin et al. · Nature Communications · 2021 · 256 citations · Full text

Life Sciences, Cell Biology, Oncology +17

HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron

Rashi Singhal, Sreedhar R. Mitta, Nupur K. Das et al. · Journal of Clinical Investigation · 2021 · 210 citations · Full text

Medicine, Cancer Biology, Oncology +17

Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer

Hannah N. Bell, Amanda K. Huber, Rashi Singhal et al. · Cell Metabolism · 2022 · 172 citations · Full text

Medicine, Immunology, Oncology +12

Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells

Andrew J. Schwartz, Joshua Goyert, Sumeet Solanki et al. · Nature Metabolism · 2021 · 151 citations · Full text

Medicine, Cancer Biology, Oncology +14