Michel Surkyn

1,4-Oxazine β-Secretase 1 (BACE1) Inhibitors: From Hit Generation to Orally Bioavailable Brain Penetrant Leads

Frederik Rombouts, Gary Tresadern, Óscar Delgado et al. · Journal of Medicinal Chemistry · 2015 · 79 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Design and Synthesis of a Novel Series of Bicyclic Heterocycles As Potent γ-Secretase Modulators

François Bischoff, Didier Berthelot, Michel De Cleyn et al. · Journal of Medicinal Chemistry · 2012 · 60 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Evaluation of a Series of β-Secretase 1 Inhibitors Containing Novel Heteroaryl-Fused-Piperazine Amidine Warheads

Daniel Oehlrich, Aldo Peschiulli, Gary Tresadern et al. · ACS Medicinal Chemistry Letters · 2019 · 38 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

5-Sulfonyl-benzimidazoles as selective CB2 agonists-Part 2

Harrie J. M. Gijsen, Michel A.J. De Cleyn, Michel Surkyn et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 30 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +7

5-Sulfonyl-benzimidazoles as selective CB2 agonists

Bie Verbist, Michel A.J. De Cleyn, Michel Surkyn et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 30 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9