Didier Berthelot

2-Amino-3,4-dihydroquinazolines as Inhibitors of BACE-1 (β-Site APP Cleaving Enzyme):  Use of Structure Based Design to Convert a Micromolar Hit into a Nanomolar Lead

Ellen W. Baxter, Kelly A. Conway, Ludo Kennis et al. · Journal of Medicinal Chemistry · 2007 · 145 citations · Full text

Combinatorial Chemistry, Drug Target, Chemical Biology +19

Analogues of Morphanthridine and the Tear Gas Dibenz[<i>b</i>,<i>f</i>][1,4]oxazepine (CR) as Extremely Potent Activators of the Human Transient Receptor Potential Ankyrin 1 (TRPA1) Channel

Harrie J. M. Gijsen, Didier Berthelot, Mirko Zaja et al. · Journal of Medicinal Chemistry · 2010 · 93 citations · Full text

Drug Target, Pharmacotherapy, Experimental Pharmacology +19

The accelerated development of an optimized synthesis of 1,2,4-oxadiazoles: application of microwave irradiation and statistical design of experiments

Marc D Evans, Jessica Ring, Adam Schoen et al. · Tetrahedron Letters · 2003 · 77 citations

Combinatorial Chemistry, Experimental Synthesis, Chemical Engineering +11

Minisci-Photoredox-Mediated α-Heteroarylation of N-Protected Secondary Amines: Remarkable Selectivity of Azetidines

Cyril Bosset, Hélène Beucher, Guillaume Bretel et al. · Organic Letters · 2018 · 74 citations

Ruthenium‐Catalyzed α‐(Hetero)Arylation of Saturated Cyclic Amines: Reaction Scope and Mechanism

Aldo Peschiulli, Veerle Smout, Thomas E. Storr et al. · Chemistry - A European Journal · 2013 · 60 citations