Michael J. Primiano

Identification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived Hit

Paul V. Fish, P. Filippakopoulos, Gerwyn Bish et al. · Journal of Medicinal Chemistry · 2012 · 196 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice

Isis Ludwig‐Portugall, Eva Bartok, Ermanila Dhana et al. · Kidney International · 2016 · 191 citations · Full text

Medicine, Immunology, Pathology +14

Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation

Michael J. Primiano, Bruce A. Lefker, Michael Bowman et al. · The Journal of Immunology · 2016 · 178 citations

Life Sciences, Immunology, Pharmacology +17

Differential neuronal and astrocytic expression of transforming growth factor beta isoforms in rat hippocampus following transient forebrain ischemia

N. Knuckey, Paul W. Finch, Donald E. Palm et al. · Molecular Brain Research · 1996 · 128 citations

Life Sciences, Neurobiology, Neuroscience +11

Cystatin C, a protease inhibitor, in degenerating rat hippocampal neurons following transient forebrain ischemia

Donald E. Palm, Neville W. Knuckey, Michael J. Primiano et al. · Brain Research · 1995 · 92 citations

Life Sciences, Neurobiology, Neuroscience +16