Bruce A. Lefker

SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids

Jitske Jansen, Katharina C. Reimer, James S. Nagai et al. · Cell stem cell · 2021 · 266 citations · Full text

Medicine, Infectious Diseases, Pathology +17

An EP2 receptor-selective prostaglandin E ₂ agonist induces bone healing

Vishwas Paralkar, Fran Borovečki, H.Z. Ke et al. · Proceedings of the National Academy of Sciences · 2003 · 186 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation

Michael J. Primiano, Bruce A. Lefker, Michael Bowman et al. · The Journal of Immunology · 2016 · 178 citations

Life Sciences, Immunology, Pharmacology +17

Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay

J. Perry Hall, Amy Brault, Fabien Vincent et al. · PLoS ONE · 2017 · 162 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

A Novel, Non-Prostanoid EP2 Receptor-Selective Prostaglandin E2 Agonist Stimulates Local Bone Formation and Enhances Fracture Healing

Mei Li, Hua Zhu Ke, Hong Qi et al. · Journal of Bone and Mineral Research · 2003 · 116 citations

Medicine, Pharmacology, Bone Metabolism +16