Dunja D. Messing

Loss of Function in Phenylketonuria Is Caused by Impaired Molecular Motions and Conformational Instability

Søren W. Gersting, Kristina Kemter, Michael Staudigl et al. · The American Journal of Human Genetics · 2008 · 122 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

The interplay between genotype, metabolic state and cofactor treatment governs phenylalanine hydroxylase function and drug response

Michael Staudigl, Søren W. Gersting, Marta K. Danecka et al. · Human Molecular Genetics · 2011 · 79 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

Protein misfolding is the molecular mechanism underlying MCADD identified in newborn screening

Esther M. Maier, Søren W. Gersting, Kristina Kemter et al. · Human Molecular Genetics · 2009 · 54 citations · Full text

Life Sciences, Biochemistry, Genetics +17

Pah enu1 is a mouse model for tetrahydrobiopterin-responsive phenylalanine hydroxylase deficiency and promotes analysis of the pharmacological chaperone mechanism in vivo

Søren W. Gersting, Florian B. Lagler, Anna Eichinger et al. · Human Molecular Genetics · 2010 · 51 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Activation of Phenylalanine Hydroxylase Induces Positive Cooperativity toward the Natural Cofactor

Søren W. Gersting, Michael Staudigl, Marietta Truger et al. · Journal of Biological Chemistry · 2010 · 36 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17