Michael Staudigl

Loss of Function in Phenylketonuria Is Caused by Impaired Molecular Motions and Conformational Instability

Søren W. Gersting, Kristina Kemter, Michael Staudigl et al. · The American Journal of Human Genetics · 2008 · 120 citations · Full text

Biophysical Modeling, Protein Function, Biochemistry +12

Pah enu1 is a mouse model for tetrahydrobiopterin-responsive phenylalanine hydroxylase deficiency and promotes analysis of the pharmacological chaperone mechanism in vivo

Søren W. Gersting, Florian B. Lagler, Anna Eichinger et al. · Human Molecular Genetics · 2010 · 50 citations · Full text

Molecular Pharmacology, Protein Function, Aldo-keto Reductase +12

Activation of Phenylalanine Hydroxylase Induces Positive Cooperativity toward the Natural Cofactor

Søren W. Gersting, Michael Staudigl, Marietta Truger et al. · Journal of Biological Chemistry · 2010 · 34 citations · Full text

Steady State Kinetics, Aldehyde Dehydrogenase, Biochemistry +13

Neurological Sequelae due to Inborn Metabolic Diseases in Pediatric Refugees: Challenges in Treating the Untreated

Katharina A. Schiergens, Michael Staudigl, Ingo Borggraefe et al. · Neuropediatrics · 2018 · 17 citations

New insights into tetrahydrobiopterin pharmacodynamics from Pahenu1/2, a mouse model for compound heterozygous tetrahydrobiopterin-responsive phenylalanine hydroxylase deficiency

Florian B. Lagler, Søren W. Gersting, Clemens Zsifkovits et al. · Biochemical Pharmacology · 2010 · 14 citations · Full text

Biochemistry, Biochemical Genetics, Tetrahydrobiopterin Pharmacodynamics +4