Marta K. Danecka

Loss of Function in Phenylketonuria Is Caused by Impaired Molecular Motions and Conformational Instability

Søren W. Gersting, Kristina Kemter, Michael Staudigl et al. · The American Journal of Human Genetics · 2008 · 120 citations · Full text

Biophysical Modeling, Protein Function, Biochemistry +12

The interplay between genotype, metabolic state and cofactor treatment governs phenylalanine hydroxylase function and drug response

Michael Staudigl, Søren W. Gersting, Marta K. Danecka et al. · Human Molecular Genetics · 2011 · 77 citations · Full text

Pah enu1 is a mouse model for tetrahydrobiopterin-responsive phenylalanine hydroxylase deficiency and promotes analysis of the pharmacological chaperone mechanism in vivo

Søren W. Gersting, Florian B. Lagler, Anna Eichinger et al. · Human Molecular Genetics · 2010 · 50 citations · Full text

Molecular Pharmacology, Protein Function, Aldo-keto Reductase +12

Mapping the functional landscape of frequent <i>phenylalanine hydroxylase</i> (<i>PAH</i>) genotypes promotes personalised medicine in phenylketonuria

Marta K. Danecka, Mathias Woidy, Johannes Zschocke et al. · Journal of Medical Genetics · 2015 · 44 citations

Activation of Phenylalanine Hydroxylase Induces Positive Cooperativity toward the Natural Cofactor

Søren W. Gersting, Michael Staudigl, Marietta Truger et al. · Journal of Biological Chemistry · 2010 · 34 citations · Full text

Steady State Kinetics, Aldehyde Dehydrogenase, Biochemistry +13