Simone Hansmann

IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results

Alison Margolskee, Adam S. Darwich, Xavier Pépin et al. · European Journal of Pharmaceutical Sciences · 2016 · 66 citations · Full text

Pharmacokinetic Modeling, Medicine, Process Analytical Technology +6

IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes

Adam S. Darwich, Alison Margolskee, Xavier Pépin et al. · European Journal of Pharmaceutical Sciences · 2016 · 45 citations · Full text

Systems Pharmacology, Silico Performance, Pharmacokinetic Modeling +13

Forecasting oral absorption across biopharmaceutics classification system classes with physiologically based pharmacokinetic models

Simone Hansmann, Adam S. Darwich, Alison Margolskee et al. · Journal of Pharmacy and Pharmacology · 2016 · 35 citations

An in silico approach to determine challenges in the bioavailability of ciprofloxacin, a poorly soluble weak base with borderline solubility and permeability characteristics

Simone Hansmann, Yoshihiro Miyaji, Jennifer Dressman · European Journal of Pharmaceutics and Biopharmaceutics · 2017 · 33 citations

Biochemistry, Silico Approach, Medicine +8

Integration of advanced methods and models to study drug absorption and related processes: An UNGAP perspective

Clive Wilson, Leon Aarons, Patrick Augustijns et al. · European Journal of Pharmaceutical Sciences · 2021 · 21 citations · Full text

Ungap Perspective, Drug Disposition, Gastroenterology +17