Jonathan Lippy

Discovery of <i>N</i>-(4-(2-Amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a Selective and Orally Efficacious Inhibitor of the Met Kinase Superfamily

Gretchen M. Schroeder, Yongmi An, Zhen‐Wei Cai et al. · Journal of Medicinal Chemistry · 2009 · 277 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Discovery of Pyrrolopyridine−Pyridone Based Inhibitors of Met Kinase: Synthesis, X-ray Crystallographic Analysis, and Biological Activities

Kyoung Soon Kim, Liping Zhang, Robert J. Schmidt et al. · Journal of Medicinal Chemistry · 2008 · 123 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain

Walter A. Kostich, Brian D. Hamman, Kumaran Dandapani et al. · Journal of Pharmacology and Experimental Therapeutics · 2016 · 120 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core

Prasanna Sivaprakasam, Xiaojun Han, Rita L. Civiello et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 116 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +16

Trends in Kinase Selectivity: Insights for Target Class-Focused Library Screening

Shana Posy, Mark A. Hermsmeier, Wayne Vaccaro et al. · Journal of Medicinal Chemistry · 2010 · 80 citations

Pharmacy, Chemical Biology, Medicinal Chemistry +15