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Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core

Combinatorial ChemistryMedicinal ChemistryBiochemistryNatural SciencesMedicineChemical SpaceRational Drug DesignHeterocycle ChemistryChemical BiologyPharmacologyNew AcylaminopyridinesDrug DiscoveryGsk-3 Inhibitors