Prasanna Sivaprakasam

Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core

Prasanna Sivaprakasam, Xiaojun Han, Rita L. Civiello et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 114 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +10

Structure−Activity Relationship and Mechanism of Action Studies of Manzamine Analogues for the Control of Neuroinflammation and Cerebral Infections

Jiangnan Peng, Sucheta Kudrimoti, Prasanna Sivaprakasam et al. · Journal of Medicinal Chemistry · 2009 · 90 citations

Discovery of Isonicotinamides as Highly Selective, Brain Penetrable, and Orally Active Glycogen Synthase Kinase-3 Inhibitors

Guanglin Luo, Ling Chen, Catherine R. Burton et al. · Journal of Medicinal Chemistry · 2016 · 68 citations · Full text

Chemoprevention Strategy, Kinase-selective Gsk-3 Inhibitors, Pharmacotherapy +16

Homology models of the <scp>HIV</scp>‐1 attachment inhibitor <scp>BMS</scp>‐626529 bound to gp120 suggest a unique mechanism of action

David R. Langley, S. Roy Kimura, Prasanna Sivaprakasam et al. · Proteins Structure Function and Bioinformatics · 2014 · 58 citations · Full text

Signal Transduction, Hiv-1 Gp120, Protein Folding +14

Probing the physicochemical and structural requirements for glycogen synthase kinase-3α inhibition: 2D-QSAR for 3-anilino-4-phenylmaleimides

Prasanna Sivaprakasam, Aihua Xie, Robert J. Doerksen · Bioorganic & Medicinal Chemistry · 2006 · 43 citations

Medicinal Chemistry, Biochemistry, Structural Requirements +8