Catherine R. Burton

Discovery and Evaluation of BMS-708163, a Potent, Selective and Orally Bioavailable γ-Secretase Inhibitor

Kevin W. Gillman, John E. Starrett, Michael F. Parker et al. · ACS Medicinal Chemistry Letters · 2010 · 183 citations

Pharmaceutical Science, Pharmacotherapy, Pharmaceutical Chemistry +19

Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core

Prasanna Sivaprakasam, Xiaojun Han, Rita L. Civiello et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 114 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +10

Synthesis and Biological Evaluation of 1-Aryl-4,5-dihydro-1<i>H</i>-pyrazolo[3,4-<i>d</i>]pyrimidin-4-one Inhibitors of Cyclin-Dependent Kinases

Jay A. Markwalder, Marc R. Arnone, Pamela A. Benfield et al. · Journal of Medicinal Chemistry · 2004 · 100 citations · Full text

High-throughput Screening Strategy, Drug Target, Molecular Biology +18

Quinazolines as cyclin dependent kinase inhibitors

Thais M. Sielecki, Tricia L. Johnson, Jie Liu et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 85 citations · Full text

Medicinal Chemistry, Medicine, Mechanism Of Action +6

Indenopyrazoles as Novel Cyclin Dependent Kinase (CDK) Inhibitors

David A. Nugiel, Ana-Marie Etzkorn, Anup Vidwans et al. · Journal of Medicinal Chemistry · 2001 · 77 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Molecular Sciences +15