Catherine R. Burton

Discovery and Evaluation of BMS-708163, a Potent, Selective and Orally Bioavailable γ-Secretase Inhibitor

Kevin W. Gillman, John E. Starrett, Michael F. Parker et al. · ACS Medicinal Chemistry Letters · 2010 · 186 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Discovery of new acylaminopyridines as GSK-3 inhibitors by a structure guided in-depth exploration of chemical space around a pyrrolopyridinone core

Prasanna Sivaprakasam, Xiaojun Han, Rita L. Civiello et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 116 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +16

Synthesis and Biological Evaluation of 1-Aryl-4,5-dihydro-1<i>H</i>-pyrazolo[3,4-<i>d</i>]pyrimidin-4-one Inhibitors of Cyclin-Dependent Kinases

Jay A. Markwalder, Marc R. Arnone, Pamela A. Benfield et al. · Journal of Medicinal Chemistry · 2004 · 102 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Quinazolines as cyclin dependent kinase inhibitors

Thais M. Sielecki, Tricia L. Johnson, Jie Liu et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 86 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10

Indenopyrazoles as Novel Cyclin Dependent Kinase (CDK) Inhibitors

David A. Nugiel, Ana-Marie Etzkorn, Anup Vidwans et al. · Journal of Medicinal Chemistry · 2001 · 77 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9