APOBEC3A catalyzes mutation and drives carcinogenesis in vivo

Emily K. Law, Rena Levin-Klein, Matthew C. Jarvis, +16

The Journal of Experimental Medicine

Somatic VariantOncogenic AgentMedicineApobec3 FamilyPathology +10

Murine leukemia virus glycosylated Gag blocks apolipoprotein B editing complex 3 and cytosolic sensor access to the reverse transcription complex

Spyridon Stavrou, Takayuki Nitta, Swathi Kotla, +5

Proceedings of the National Academy of Sciences

Nucleic Acid Recognition Orchestrates the Anti-Viral Response to Retroviruses

Spyridon Stavrou, Kristin Blouch, Swathi Kotla, +2

Cell Host & Microbe

Viral ReplicationImmunologyNucleic Acid RecognitionVirologyMedicine +1

AIM2-Like Receptors Positively and Negatively Regulate the Interferon Response Induced by Cytosolic DNA

Yuki Nakaya, Jingtao Lilue, Spyridon Stavrou, +2

mBio

DDX41 Recognizes RNA/DNA Retroviral Reverse Transcripts and Is Critical for <i>In Vivo</i> Control of Murine Leukemia Virus Infection

Spyridon Stavrou, Alexya N. Aguilera, Kristin Blouch, +1

mBio

SARS-CoV-2 ORF7a potently inhibits the antiviral effect of the host factor SERINC5

Uddhav Timilsina, Supawadee Umthong, Emily B. Ivey, +2

Nature Communications

Different Modes of Retrovirus Restriction by Human APOBEC3A and APOBEC3G In Vivo

Spyridon Stavrou, Daniel Crawford, Kristin Blouch, +3

PLoS Pathogens

Murine Leukemia VirusGeneticsImmunologyPathologyRetrovirus Restriction +16

<i>In Vivo</i> Examination of Mouse APOBEC3- and Human APOBEC3A- and APOBEC3G-Mediated Restriction of Parvovirus and Herpesvirus Infection in Mouse Models

Yuki Nakaya, Spyridon Stavrou, Kristin Blouch, +2

Journal of Virology

Elucidating the Antiviral Mechanism of Different MARCH Factors

Supawadee Umthong, Brian Lynch, Uddhav Timilsina, +3

mBio

Deaminase-Dead Mouse APOBEC3 Is an <i>In Vivo</i> Retroviral Restriction Factor

Spyridon Stavrou, Wenming Zhao, Kristin Blouch, +1

Journal of Virology