Michael Goodwin

Fumarate Reductase Activity Maintains an Energized Membrane in Anaerobic Mycobacterium tuberculosis

Shinya Watanabe, Michael Zimmermann, Michael Goodwin et al. · PLoS Pathogens · 2011 · 242 citations · Full text

Metronidazole prevents reactivation of latent<i>Mycobacterium tuberculosis</i>infection in macaques

Philana Ling Lin, Véronique Dartois, Paul Johnston et al. · Proceedings of the National Academy of Sciences · 2012 · 122 citations · Full text

Structure−Activity Relationships of Antitubercular Nitroimidazoles. 2. Determinants of Aerobic Activity and Quantitative Structure−Activity Relationships

Pilho Kim, Sun‐Hee Kang, Helena I. Boshoff et al. · Journal of Medicinal Chemistry · 2009 · 87 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +15

Structure−Activity Relationships at the 5-Position of Thiolactomycin:  An Intact (5<i>R</i>)-Isoprene Unit Is Required for Activity against the Condensing Enzymes from <i>Mycobacterium </i><i>t</i><i>uberculosis</i> and <i>Escherichia </i><i>c</i><i>oli</i>

Pilho Kim, Yongmei Zhang, Gautham G. Shenoy et al. · Journal of Medicinal Chemistry · 2005 · 80 citations · Full text

Synthesis and antitubercular activity of 7-(R)- and 7-(S)-methyl-2-nitro-6-(S)-(4-(trifluoromethoxy)benzyloxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazines, analogues of PA-824

Xiaojin Li, Ujjini H. Manjunatha, Michael Goodwin et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 68 citations · Full text

Antitubercular Activity, Bioorganic Chemistry, Heterocyclic +9