Robert C.C. Mercer

Prions activate a p38 MAPK synaptotoxic signaling pathway

Bei Wu, Nhat T. T. Le, Thibaut Imberdis et al. · PLoS Pathogens · 2018 · 77 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

The Prion Protein Modulates A-type K+ Currents Mediated by Kv4.2 Complexes through Dipeptidyl Aminopeptidase-like Protein 6

Robert C.C. Mercer, Li Ma, Joel C. Watts et al. · Journal of Biological Chemistry · 2013 · 31 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation

Agnes Lau, Alex J. McDonald, Nathalie Daude et al. · EMBO Molecular Medicine · 2015 · 31 citations · Full text

Veterinary Medicine, Biochemistry, Molecular Biology +15

Endoproteolytic processing of the mammalian prion glycoprotein family

Charles E. Mays, Janaky Coomaraswamy, Joel C. Watts et al. · FEBS Journal · 2013 · 26 citations

Life Sciences, Genetics, Prion Diseases +14

A novel Gerstmann-Sträussler-Scheinker disease mutation defines a precursor for amyloidogenic 8 kDa PrP fragments and reveals N-terminal structural changes shared by other GSS alleles

Robert C.C. Mercer, Nathalie Daude, Lyudmyla Dorosh et al. · PLoS Pathogens · 2018 · 25 citations · Full text

Veterinary Medicine, Genetics, Neurology +17