Discovery of a New Boron-Containing Antifungal Agent, 5-Fluoro-1,3-dihydro-1-hydroxy-2,1- benzoxaborole (AN2690), for the Potential Treatment of Onychomycosis

Stephen J. Baker, Yong-Kang Zhang, Tsutomu Akama, +7

Journal of Medicinal Chemistry

5-Fluoro-1,3-dihydro-1-hydroxy-2,1- BenzoxaboroleMedicinal ChemistryAntifungal AgentAntifungal AgentsMedicine +9

Canonical WNT/β-catenin signaling is required for ureteric branching

Darren Bridgewater, Brian Cox, Jason E. Cain, +6

Developmental Biology

UrologySignal TransductionDevelopmental BiologyMolecular PhysiologyCanonical Wnt/β-catenin Signaling +7

Interactome Analyses Identify Ties of PrPC and Its Mammalian Paralogs to Oligomannosidic N-Glycans and Endoplasmic Reticulum-Derived Chaperones

Joel C. Watts, Hai-ru Huo, Yu Bai, +11

PLoS Pathogens

Mammalian ParalogsFamily MembersMolecular BiologyCytoskeletonCellular Physiology +21

Prion Infections and Anti-PrP Antibodies Trigger Converging Neurotoxic Pathways

U. Herrmann, Tiziana Sonati, Jeppe Falsig, +10

PLoS Pathogens

Creutzfeldt-jakob DiseaseImmunologyCell DeathPrion InfectionsOxidative Stress +14

Prion disease tempo determined by host-dependent substrate reduction

Charles E. Mays, Chae Kim, Tracy Haldiman, +12

Journal of Clinical Investigation

Creutzfeldt-jakob DiseaseSheep ScrapieMedicineNatural SciencesPathogenesis +8

Synaptic localization of C9orf72 regulates post-synaptic glutamate receptor 1 levels

Shangxi Xiao, Paul M. McKeever, Agnes Lau, +1

Acta Neuropathologica Communications

The chemistry of gut microbiome in health and diseases

Agnes Lau, Loh Teng‐Hern Tan, Nurul‐Syakima Ab Mutalib, +3

Progress In Microbes & Molecular Biology

ProbioticDysbiosisMicrobiotaGut MicrobiologyProbiotics +12

Down-Regulation of Shadoo in Prion Infections Traces a Pre-Clinical Event Inversely Related to PrPSc Accumulation

David Westaway, Sacha Genovesi, Nathalie Daude, +15

PLoS Pathogens

Factors Predictive of Significant Hepatic Fibrosis in Adults With Chronic Hepatitis B and Normal Serum ALT

Chia C. Wang, Lei Y. Lim, Heike Deubner, +6

Journal of Clinical Gastroenterology

Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation

Agnes Lau, Alex J. McDonald, Nathalie Daude, +17

EMBO Molecular Medicine

MedicineGeneticsPhysiologyOctarepeat Region FlexibilityPrion Disease +2