Concepedia

Alex J. McDonald

AJ

8

Publications

414

Citations

8

H-Index

2011

Active since

Affiliations

University of California, Santa Cruz(Current)

University of Saskatchewan

Boston University

Alex J. McDonald is an author at University of California, Santa Cruz specializing in medicine, natural sciences, and molecular biology.

ORCID

Top concepts

Publications per year

2011–2019

8

Publications

8

A New Paradigm for Enzymatic Control of α-Cleavage and β-Cleavage of the Prion Protein

Alex J. McDonald, Jessie P. Dibble, Eric G.B. Evans et al. · Journal of Biological Chemistry · 2013 · 101 citations · Full text

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Copper Redox Cycling in the Prion Protein Depends Critically on Binding Mode

Lin Liu, Dianlu Jiang, Alex J. McDonald et al. · Journal of the American Chemical Society · 2011 · 91 citations · Full text

The N-terminus of the prion protein is a toxic effector regulated by the C-terminus

Bei Wu, Alex J. McDonald, Kathleen Markham et al. · eLife · 2017 · 84 citations · Full text

Altered Domain Structure of the Prion Protein Caused by Cu2+ Binding and Functionally Relevant Mutations: Analysis by Cross-Linking, MS/MS, and NMR

Alex J. McDonald, Deborah R. Leon, Kathleen Markham et al. · Structure · 2019 · 36 citations · Full text

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Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation

Agnes Lau, Alex J. McDonald, Nathalie Daude et al. · EMBO Molecular Medicine · 2015 · 30 citations · Full text

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