Momordin Ic couples apoptosis with autophagy in human hepatoblastoma cancer cells by reactive oxygen species (ROS)-mediated PI3K/Akt and MAPK signaling pathways

Yashi Mi, Chunxia Xiao, Qingwei Du, +3

Free Radical Biology and Medicine

Cell AutophagyMitophagyMomordin IcSignaling PathwayMedicine +12

Astaxanthin alleviates brain aging in rats by attenuating oxidative stress and increasing BDNF levels

Wanqiang Wu, Xin Wang, Qisen Xiang, +7

Food & Function

AgingLipid PeroxidationRedox BiologyOxidative StressAlzheimer's Disease +14

Lutein suppresses inflammatory responses through Nrf2 activation and NF‐κB inactivation in lipopolysaccharide‐stimulated BV‐2 microglia

Wanqiang Wu, Yuelian Li, Yue Wu, +3

Molecular Nutrition & Food Research

Acrylamide induces mitochondrial dysfunction and apoptosis in BV-2 microglial cells

Zhigang Liu, Ge Song, Chen Zou, +4

Free Radical Biology and Medicine

InflammationMitochondrial DysfunctionMedicineApoptosisImmunology +7

MAPK signaling pathways regulate mitochondrial-mediated apoptosis induced by isoorientin in human hepatoblastoma cancer cells

Yuan Li, Jing Wang, Haifang Xiao, +3

Food and Chemical Toxicology

MitophagyMitochondrial-mediated ApoptosisChemoprevention StrategyMitochondrial FunctionApoptosis +9

Chicoric acid prevents obesity by attenuating hepatic steatosis, inflammation and oxidative stress in high-fat diet-fed mice

Haifang Xiao, Guo Xie, Jiawei Wang, +4

Food Research International

ObesityMetabolic SyndromeNutritionLipid NutritionMedicine +9

Carnosic acid attenuates lipopolysaccharide-induced liver injury in rats via fortifying cellular antioxidant defense system

Qisen Xiang, Zhigang Liu, Yutang Wang, +4

Food and Chemical Toxicology

InflammationHepatologyBiochemistryHealth SciencesMedicine +10

Advances in enhancing the mechanical properties of biopolymer hydrogels via multi-strategic approaches

Xiaojia Yan, Hechun Huang, Amr M. Bakry, +3

International Journal of Biological Macromolecules

BDNF inhibits neurodegenerative disease–associated asparaginyl endopeptidase activity via phosphorylation by AKT

Zhi-Hao Wang, Wanqiang Wu, Seong Su Kang, +9

JCI Insight

MitophagyResidue T322Asparaginyl Endopeptidase ActivityCell DeathNeurochemical Biomarkers +24

Effect of isoorientin on intracellular antioxidant defence mechanisms in hepatoma and liver cell lines

Yuan Li, Jing Wang, Wanqiang Wu, +2

Biomedicine & Pharmacotherapy

HepatologyBiochemistryHealth SciencesMedicineLiver Physiology +9