Inhibition of the aryl hydrocarbon receptor prevents Western diet-induced obesity. Model for AHR activation by kynurenine via oxidized-LDL, TLR2/4, TGFβ, and IDO1

Benjamin Moyer, Itzel Y. Rojas, Joanna S. Kerley-Hamilton, +10

Toxicology and Applied Pharmacology

ObesityMetabolic SyndromeAhr ActivationMetabolic DisorderBiochemistry +6

Obesity Is Mediated by Differential Aryl Hydrocarbon Receptor Signaling in Mice Fed a Western Diet

Joanna S. Kerley-Hamilton, Heidi W. Trask, C. Ridley, +10

Environmental Health Perspectives

Inherent and Benzo[a]pyrene-Induced Differential Aryl Hydrocarbon Receptor Signaling Greatly Affects Life Span, Atherosclerosis, Cardiac Gene Expression, and Body and Heart Growth in Mice

Joanna S. Kerley-Hamilton, Heidi W. Trask, C. Ridley, +9

Toxicological Sciences

Environmental SignalingGrowth RatesCardiovascular ToxicityToxicological MechanismOxidative Stress +14

Obesity and fatty liver are prevented by inhibition of the aryl hydrocarbon receptor in both female and male mice

Benjamin Moyer, Itzel Y. Rojas, Joanna S. Kerley-Hamilton, +6

Nutrition Research

ObesityMetabolic SyndromeBiochemistryMedicineLiver Physiology +11

miRNAs in Newt Lens Regeneration: Specific Control of Proliferation and Evidence for miRNA Networking

Kenta Nakamura, Nobuyasu Maki, Albert Trinh, +4

PLoS ONE

ARSENITE DECREASES CYP3A4 AND RXRα IN PRIMARY HUMAN HEPATOCYTES

Trisha L. Noreault, Vsevolod E. Kostrubsky, Sheryl G. Wood, +8

Drug Metabolism and Disposition

Microarray analysis of cytoplasmic versus whole cell RNA reveals a considerable number of missed and false positive mRNAs

Heidi W. Trask, Richard Cowper‐Sal·lari, Maureen A. Sartor, +8

RNA

EngineeringGeneticsMicroarray StudyFalse Positive MrnasTranscriptomics Technology +17

Uroporphyria caused by ethanol in Hfe (−/−) mice as a model for porphyria cutanea tarda

Peter R. Sinclair, Nadia Gorman, Heidi W. Trask, +6

Hepatology

Arsenite decreases CYP3A23 induction in cultured rat hepatocytes by transcriptional and translational mechanisms

Trisha L. Noreault, Judith M. Jacobs, Ralph C. Nichols, +5

Toxicology and Applied Pharmacology

Transcriptional RegulationDevelopmental BiologyMedicineLiver PhysiologyCell Death +7

Arsenic decreases RXRα-dependent transcription of CYP3A and suppresses immune regulators in hepatocytes

Trisha L. Noreault-Conti, Abigail M. Fellows, Judith M. Jacobs, +7

International Immunopharmacology

InflammationTranscriptional RegulationImmune RegulatorsRxrα-dependent TranscriptionLiver Physiology +8