Concepedia

Inhibition of the aryl hydrocarbon receptor prevents Western diet-induced obesity. Model for AHR activation by kynurenine via oxidized-LDL, TLR2/4, TGFβ, and IDO1

Benjamin Moyer, Itzel Y. Rojas, Joanna S. Kerley-Hamilton, Haley F. Hazlett, Krishnamurthy V. Nemani, Heidi W. Trask, Rachel J. West, Leslie Lupien, Alan J. Collins, Carol S. Ringelberg,

Toxicology and Applied Pharmacology · 2016 · 124 citations · 67 references

DOI

Concepts

References

67

Positional cloning of the mouse obese gene and its human homologue

Yiying Zhang, Ricardo Proenca, Margherita Maffei et al. · Nature · 1994 · 13.4K citations

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Prevalence of Childhood and Adult Obesity in the United States, 2011-2012

Cynthia L. Ogden, Margaret D. Carroll, Brian K. Kit et al. · JAMA · 2014 · 8.1K citations · Full text

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The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

Toshimasa Yamauchi, Junji Kamon, Hironori Waki et al. · Nature Medicine · 2001 · 4.9K citations

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Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

Francisco J. Quintana, Alexandre S. Basso, Antonio Iglesias et al. · Nature · 2008 · 1.8K citations

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An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

Joshua D. Mezrich, John H. Fechner, Xiaoji Zhang et al. · The Journal of Immunology · 2010 · 1.6K citations · Full text

, , +15