Pedro A. Mateos‐Gómez

Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination

Pedro A. Mateos‐Gómez, Fade Gong, Nidhi Nair et al. · Nature · 2015 · 723 citations · Full text

Transcriptional Regulation, Mammalian Polymerase θ, Natural Sciences +5

Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR–Cas9 genome-editing efficiency

Marella D. Canny, Nathalie Moatti, Leo C. K. Wan et al. · Nature Biotechnology · 2017 · 286 citations · Full text

Chromatin, Genome Instability, Genetics +7

Coronavirus Nucleocapsid Protein Facilitates Template Switching and Is Required for Efficient Transcription

Sonia Zúñiga, Jazmina L. Gonzalez Cruz, Isabel Sola et al. · Journal of Virology · 2009 · 229 citations · Full text

Viral Replication, N Protein, Genetics +18

The helicase domain of Polθ counteracts RPA to promote alt-NHEJ

Pedro A. Mateos‐Gómez, Tatiana Kent, Sarah Deng et al. · Nature Structural & Molecular Biology · 2017 · 189 citations · Full text

Helicase Domain, Signal Transduction, Biochemistry +4

Polymerase θ is a robust terminal transferase that oscillates between three different mechanisms during end-joining

Tatiana Kent, Pedro A. Mateos‐Gómez, Agnel Sfeir et al. · eLife · 2016 · 104 citations · Full text