Tatiana Kent

Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ

Tatiana Kent, Gurushankar Chandramouly, Shane McDevitt et al. · Nature Structural & Molecular Biology · 2015 · 330 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

The helicase domain of Polθ counteracts RPA to promote alt-NHEJ

Pedro A. Mateos‐Gómez, Tatiana Kent, Sarah Deng et al. · Nature Structural & Molecular Biology · 2017 · 193 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +4

Molecular basis of microhomology-mediated end-joining by purified full-length Polθ

Samuel J. Black, Ahmet Y. Ozdemir, Ekaterina Kashkina et al. · Nature Communications · 2019 · 116 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Polymerase θ is a robust terminal transferase that oscillates between three different mechanisms during end-joining

Tatiana Kent, Pedro A. Mateos‐Gómez, Agnel Sfeir et al. · eLife · 2016 · 108 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Polθ reverse transcribes RNA and promotes RNA-templated DNA repair

Gurushankar Chandramouly, Jiemin Zhao, Shane McDevitt et al. · Science Advances · 2021 · 104 citations · Full text

Life Sciences, Biology, Molecular Biology +8