Nathan P. Coussens

Isolation of an endotoxin–MD-2 complex that produces Toll-like receptor 4-dependent cell activation at picomolar concentrations

Theresa L. Gioannini, Athmane Teghanemt, Desheng Zhang et al. · Proceedings of the National Academy of Sciences · 2004 · 362 citations · Full text

Assay Guidance Manual [Internet]

Sarine Markossian, A Grossman, Kyle R. Brimacombe et al. · 2004 · 287 citations

Pharmaceutical Research, Drug Target, Biochemistry +15

Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy

William C. Stafford, Xiaoxiao Peng, Maria Hägg Olofsson et al. · Science Translational Medicine · 2018 · 229 citations · Full text

Ablation of Smurf2 reveals an inhibition in TGF‐β signalling through multiple mono‐ubiquitination of Smad3

Liu-Ya Tang, Motozo Yamashita, Nathan P. Coussens et al. · The EMBO Journal · 2011 · 132 citations · Full text

AlphaScreen-Based Assays: Ultra-High-Throughput Screening for Small-Molecule Inhibitors of Challenging Enzymes and Protein-Protein Interactions

Adam Yasgar, Ajit Jadhav, Anton Simeonov et al. · Methods in molecular biology · 2016 · 123 citations · Full text

Molecular Docking, Drug Target, Biochemistry +12