Lyndsey Bolanos

U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies

Molly A. Smith, Gaurav S. Choudhary, Andrea Pellagatti et al. · Nature Cell Biology · 2019 · 243 citations

Hematological Malignancy, Innate Immune Pathways, Medicine +8

Targeting IRAK1 as a Therapeutic Approach for Myelodysplastic Syndrome

Garrett W. Rhyasen, Lyndsey Bolanos, Jing Fang et al. · Cancer Cell · 2013 · 199 citations · Full text

Hematological Malignancy, Myelodysplastic Syndrome, Immunology +4

Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1

Jing Fang, Garrett W. Rhyasen, Lyndsey Bolanos et al. · Blood · 2012 · 100 citations · Full text

Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia

Jing Fang, Lyndsey Bolanos, Kwangmin Choi et al. · Nature Immunology · 2016 · 96 citations · Full text

Signal Transduction, Signaling Pathway, Immunology +6

Overcoming adaptive therapy resistance in AML by targeting immune response pathways

Katelyn Melgar, Morgan M. Walker, LaQuita M. Jones et al. · Science Translational Medicine · 2019 · 86 citations · Full text