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Cancer Research

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U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies

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Nature Cell Biology

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iPS cell modeling of Best disease: insights into the pathophysiology of an inherited macular degeneration

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Human Molecular Genetics

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Adaptive response to inflammation contributes to sustained myelopoiesis and confers a competitive advantage in myelodysplastic syndrome HSCs

Tomoya Muto, Callum S. Walker, Kwangmin Choi, +7

Nature Immunology

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Functional Analysis of Serially Expanded Human iPS Cell-Derived RPE Cultures

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Investigative Ophthalmology & Visual Science

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Clinical Cancer Research

Activation of targetable inflammatory immune signaling is seen in myelodysplastic syndromes with SF3B1 mutations

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eLife

Combined inhibition of EGFR and c-ABL suppresses the growth of triple-negative breast cancer growth through inhibition of <i>HOTAIR</i>

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Oncotarget

Pharmacological Modulation of Photoreceptor Outer Segment Degradation in a Human iPS Cell Model of Inherited Macular Degeneration

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Molecular Therapy

Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia

Laura Barreyro, Avery Sampson, Chiharu Ishikawa, +31

Science Translational Medicine

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