Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Aravind Subramanian, Pablo Tamayo, Vamsi K. Mootha, +8

Proceedings of the National Academy of Sciences

GeneticsGenomicsGene RecognitionBioinformatics DatabaseGene Expression Profiling +21

International Scoring System for Evaluating Prognosis in Myelodysplastic Syndromes

Peter L. Greenberg, Christopher Cox, Michelle M. LeBeau, +12

Blood

NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

Konstantin D. Taganov, Mark Boldin, Kuang‐Jung Chang, +1

Proceedings of the National Academy of Sciences

Innate Immune SystemImmune RegulationImmunologyReporter GeneInnate Immunity +20

ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

Jing Chen, Eric E. Bardes, Bruce J. Aronow, +1

Nucleic Acids Research

Oncogenically active MYD88 mutations in human lymphoma

Vu N. Ngo, Ryan M. Young, Roland Schmitz, +28

Nature

Tumor BiologyLymphoid NeoplasiaPathologyActive Myd88 MutationsMedicine +1

<i>miR-146a</i> is a significant brake on autoimmunity, myeloproliferation, and cancer in mice

Mark Boldin, Konstantin D. Taganov, Dinesh S. Rao, +11

The Journal of Experimental Medicine

ImmunologyImmune RegulationPathologyInnate ImmunityImmune System +19

Identification of miR-145 and miR-146a as mediators of the 5q– syndrome phenotype

Daniel T. Starczynowski, Florian Kuchenbauer, Bob Argiropoulos, +11

Nature Medicine

EngineeringEpigenetic RegulationMedicineGeneticsImmunology +8

NF-κB dysregulation in microRNA-146a–deficient mice drives the development of myeloid malignancies

Jimmy L. Zhao, Dinesh S. Rao, Mark Boldin, +3

Proceedings of the National Academy of Sciences

Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML

Lukasz P. Gondek, Ramón V. Tiu, Christine L. O’Keefe, +3

Blood

CytogeneticsMixed-phenotype Acute LeukemiaGeneticsPathologyEpigenetics +17

Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells

Andrea Pellagatti, Mario Cazzola, Aristoteles Giagounidis, +10

Leukemia

Developmental BiologyBone Marrow FailureMedicineStem Cell MobilizationHematology +10