Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells

Courtney L. Jones, Brett M. Stevens, Angelo D’Alessandro, +13

Cancer Cell

Hematological MalignancyBiochemistryMedicineMixed-phenotype Acute LeukemiaPharmacology +3

Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche

Haobin Ye, Biniam Adane, Nabilah Khan, +12

Cell stem cell

MedicineStem Cell MobilizationBiological MicroenvironmentsMetabolic AdaptationAdipose Tissue Niche +9

Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia

Shanshan Pei, Daniel A. Pollyea, Annika Gustafson, +29

Cancer Discovery

Mixed-phenotype Acute LeukemiaImmunologyPharmacotherapyImmunotherapyDrug Resistance +17

Fatty acid metabolism underlies venetoclax resistance in acute myeloid leukemia stem cells

Brett M. Stevens, Courtney L. Jones, Daniel A. Pollyea, +13

Nature Cancer

Hematological MalignancyMixed-phenotype Acute LeukemiaHematologyImmunologyMetabolism Underlies +4

Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells

Courtney L. Jones, Brett M. Stevens, Daniel A. Pollyea, +19

Cell stem cell

Hematological MalignancyMedicineMixed-phenotype Acute LeukemiaStem CellsHematology +5

Targeting Aberrant Glutathione Metabolism to Eradicate Human Acute Myelogenous Leukemia Cells

Shanshan Pei, Mohammad Minhajuddin, Kevin P. Callahan, +18

Journal of Biological Chemistry

Engineering Metal–Phenolic Networks for Solar Desalination with Directional Salt Crystallization

Zhenxing Wang, Jie Gao, Jiajing Zhou, +8

Advanced Materials

The STAT3-MYC axis promotes survival of leukemia stem cells by regulating SLC1A5 and oxidative phosphorylation

Maria L. Amaya, Anagha Inguva Sheth, Shanshan Pei, +12

Blood

Subversion of Systemic Glucose Metabolism as a Mechanism to Support the Growth of Leukemia Cells

Haobin Ye, Biniam Adane, Nabilah Khan, +14

Cancer Cell

Developmental BiologyMetabolic ReprogrammingLeukemia CellsMetabolic RegulationSystemic Glucose Metabolism +7

The Hematopoietic Oxidase NOX2 Regulates Self-Renewal of Leukemic Stem Cells

Biniam Adane, Haobin Ye, Nabilah Khan, +18

Cell Reports