Letian Song

Discovery and Crystallographic Studies of Trisubstituted Piperazine Derivatives as Non-Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity and Low Toxicity

Shenghua Gao, Katharina Sylvester, Letian Song et al. · Journal of Medicinal Chemistry · 2022 · 78 citations · Full text

Discovery and Crystallographic Studies of Nonpeptidic Piperazine Derivatives as Covalent SARS-CoV-2 Main Protease Inhibitors

Shenghua Gao, Letian Song, Tobias Claff et al. · Journal of Medicinal Chemistry · 2022 · 30 citations · Full text

Design, Synthesis, and Biological Evaluation of Trisubstituted Piperazine Derivatives as Noncovalent Severe Acute Respiratory Syndrome Coronavirus 2 Main Protease Inhibitors with Improved Antiviral Activity and Favorable Druggability

Shenghua Gao, Letian Song, Katharina Sylvester et al. · Journal of Medicinal Chemistry · 2023 · 26 citations · Full text

Miniaturized Modular Click Chemistry‐enabled Rapid Discovery of Unique SARS‐CoV‐2 M^pro Inhibitors With Robust Potency and Drug‐like Profile

Mianling Yang, Myoung Kyu Lee, Shenghua Gao et al. · Advanced Science · 2024 · 15 citations · Full text

Discovery of novel sulfonamide substituted indolylarylsulfones as potent HIV-1 inhibitors with better safety profiles

Shenghua Gao, Letian Song, Yusen Cheng et al. · Acta Pharmaceutica Sinica B · 2023 · 14 citations · Full text