Yusen Cheng

Discovery and Crystallographic Studies of Trisubstituted Piperazine Derivatives as Non-Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity and Low Toxicity

Shenghua Gao, Katharina Sylvester, Letian Song et al. · Journal of Medicinal Chemistry · 2022 · 83 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Discovery and Crystallographic Studies of Nonpeptidic Piperazine Derivatives as Covalent SARS-CoV-2 Main Protease Inhibitors

Shenghua Gao, Letian Song, Tobias Claff et al. · Journal of Medicinal Chemistry · 2022 · 34 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Discovery of novel sulfonamide substituted indolylarylsulfones as potent HIV-1 inhibitors with better safety profiles

Shenghua Gao, Letian Song, Yusen Cheng et al. · Acta Pharmaceutica Sinica B · 2023 · 15 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Identification of Polyphenol Derivatives as Novel SARS-CoV-2 and DENV Non-Nucleoside RdRp Inhibitors

Shenghua Gao, Letian Song, Hongtao Xu et al. · Molecules · 2022 · 13 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Indolylarylsulfones bearing phenylboronic acid and phenylboronate ester functionalities as potent HIV‑1 non-nucleoside reverse transcriptase inhibitors

Shujing Xu, Shu Song, Lin Sun et al. · Bioorganic & Medicinal Chemistry · 2021 · 12 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14