Katharina Sylvester

Targeting the Main Protease of SARS‐CoV‐2: From the Establishment of High Throughput Screening to the Design of Tailored Inhibitors

Julian Breidenbach, Carina Lemke, Thanigaimalai Pillaiyar et al. · Angewandte Chemie International Edition · 2021 · 148 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +16

Diindolylmethane Derivatives: Potent Agonists of the Immunostimulatory Orphan G Protein-Coupled Receptor GPR84

Thanigaimalai Pillaiyar, Meryem Köse, Katharina Sylvester et al. · Journal of Medicinal Chemistry · 2017 · 103 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Discovery and Crystallographic Studies of Trisubstituted Piperazine Derivatives as Non-Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity and Low Toxicity

Shenghua Gao, Katharina Sylvester, Letian Song et al. · Journal of Medicinal Chemistry · 2022 · 83 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Small-Molecule Thioesters as SARS-CoV-2 Main Protease Inhibitors: Enzyme Inhibition, Structure–Activity Relationships, Antiviral Activity, and X-ray Structure Determination

Thanigaimalai Pillaiyar, Philipp Flury, Nadine Krüger et al. · Journal of Medicinal Chemistry · 2022 · 67 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +16

6-(Ar)Alkylamino-Substituted Uracil Derivatives: Lipid Mimetics with Potent Activity at the Orphan G Protein-Coupled Receptor 84 (GPR84)

Thanigaimalai Pillaiyar, Meryem Köse, Vigneshwaran Namasivayam et al. · ACS Omega · 2018 · 37 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13