Concepedia

Alva M. Casey

AM

Statistics

Publications

6

Citations

693

H-Index

6

Active since

2022

Affiliations

MRC Mitochondrial Biology Unit(Current)

University of Cambridge

University of Glasgow

University Hospital Cologne

Trinity College Dublin

Alva M. Casey is an author at MRC Mitochondrial Biology Unit specializing in life sciences, mitochondrial physiology, and innate immunity.

ORCID

Publications per year

2022–2025

6

Publications

6

Macrophage fumarate hydratase restrains mtRNA-mediated interferon production

Alexander Hooftman, Christian G. Peace, Dylan G. Ryan et al. · Nature · 2023 · 224 citations · Full text

, , +13

Mitochondrial complex I activity in microglia sustains neuroinflammation

Luca Peruzzotti‐Jametti, Carolyn M. Willis, Grzegorz Krzak et al. · Nature · 2024 · 203 citations · Full text

, , +17

Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response

Dylan G. Ryan, Elena V. Knatko, Alva M. Casey et al. · iScience · 2022 · 106 citations · Full text

, , +14

Pro-inflammatory macrophages produce mitochondria-derived superoxide by reverse electron transport at complex I that regulates IL-1β release during NLRP3 inflammasome activation

Alva M. Casey, Dylan G. Ryan, Hiran A. Prag et al. · Nature Metabolism · 2025 · 99 citations · Full text

, , +17

Ergothioneine improves healthspan of aged animals by enhancing cGPDH activity through CSE-dependent persulfidation

Dunja Petrovic, Luke Slade, Yiorgos Paikopoulos et al. · Cell Metabolism · 2025 · 42 citations · Full text

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