Kaichuan Zhu

The Trem2 R47H Alzheimer’s risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans

Xianyuan Xiang, Thomas M. Piers, Benedikt Wefers et al. · Molecular Neurodegeneration · 2018 · 173 citations · Full text

Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibition Impairs Synaptic Plasticity via Seizure Protein 6

Kaichuan Zhu, Xianyuan Xiang, Severin Filser et al. · Biological Psychiatry · 2016 · 109 citations · Full text

Amyloid precursor protein maintains constitutive and adaptive plasticity of dendritic spines in adult brain by regulating D‐serine homeostasis

Chengyu Zou, Sophie Crux, Stéphane Marinesco et al. · The EMBO Journal · 2016 · 48 citations · Full text

Cognitive decline in Tg2576 mice shows sex-specific differences and correlates with cerebral amyloid-beta

Sebastian Schmid, Gerhard Rammes, Manfred Blobner et al. · Behavioural Brain Research · 2018 · 36 citations

Neurodegenerative Diseases, Alzheimer's Disease, Brain Function +9

The NMDA receptor antagonist Radiprodil reverses the synaptotoxic effects of different amyloid-beta (Aβ) species on long-term potentiation (LTP)

Gerhard Rammes, Franziska Seeser, Korinna Mattusch et al. · Neuropharmacology · 2018 · 32 citations

Synaptic Transmission, Synaptic Signaling, Social Sciences +17